A modified method for isolation of Rhein from Senna
Medicinal Natural Products Research Laboratory, Institute of Chemical Technology, Mumbai-400 019, India
K S Laddha Medicinal Natural Products Research Laboratory, Institute of Chemical Technology, Mumbai-400 019 India E-mail: [email protected]
A simple and efficient method for the isolation of rhein from Cassia angustifolia (senna) leaves is described in which the hydrolysis of the sennosides and extraction of the hydrolysis products (free anthraquinones) is carried out in one step. Further isolation of rhein is achieved from the anthraquinone mixture. This method reduces the number of steps required for isolation of rhein as compared to conventional methods.