A Novel Herbomineral Formulation Sahaj Vati as Shelf Life Enhancer of Nutraceuticals Based on Aflatoxin Inhibitory and Antioxidant Activity
Department of Rasa Shastra, Faculty of Ayurveda, Institute of Medical Sciences, Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu University, Varanasi-221 005, India
Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu University, Varanasi-221 005, India E-mail: [email protected]
The present investigation deals with chemical standardization and aflatoxin inhibitory and antioxidant activity of a herbomineral formulation, sahaj vati prepared in two batches (batch I and II) by mixing shilajeet (thick exudates of the mountain during summer season), guggul (Commiphora mukul (stocks) hook.), haridra (Curcuma longa L) and chitrak (Plumbago zealanica L) with levigation of Agnimantha kwatha (Premna mucronata L). Batch I was prepared by mixing shilajeet, guggul, haridra and chitrak in equal proportion (25% each by weight) while batch II comprised shilajeet (44.7%), guggul (44.7%), haridra (4.8%) and chitrak (5.8%) by weight. Sahaj vati II showed highest (96%) inhibition of aflatoxin production at concentration of 10 000 µg/ml. Suddha guggul exhibited strong antioxidant activity showing lowest IC50 at concentration of 20.56 µg/ml. Based on these findings, the newly formulated herbomineral formulation could be recommended for value addition of nutraceuticals by enhancing their shelf life against lipid per oxidation and aflatoxin contamination.