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Abstract

A rapid titrimetric method for the determination of isoniazid in drugs.

Author(s): BC Verma, S Kumar, P Kumar, DK Sharma, A Sood
Deptt. of Chemistry, Himachal Pradesh University, Simla-171 005,

Correspondence Address:
B C Verma Deptt. of Chemistry, Himachal Pradesh University, Simla-171 005

A simple, rapid and reliable method for the determination of isoniazid, based on its oxidimetric titration with lead (IV) acetate in glacial acetic acid medium, is described. The end-point may be detected visually using quinalizarin indicator or potentiometrically using platinum wire indicator electrode and modified calomel reference electrode.