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Abstract

Acrylate adhesives for transdermal therapeutic systems.

Author(s): JK Lalla, VR Bapat, VC Malshe
Dept. of Pharmaceutics, Principal K.M. Kundnani College of Pharmacy, Plot No.47, Dr. R.G. Thadani Marg, Worli Sea Face, Bombay - 400 018

Correspondence Address:
J K Lalla Dept. of Pharmaceutics, Principal K.M. Kundnani College of Pharmacy, Plot No.47, Dr. R.G. Thadani Marg, Worli Sea Face, Bombay - 400 018

Acrylate adhesives were synthesized by suspension emulsion and solution polymerization process with a view to use them in transdermal therapeutic systems. Two of the selected copolymers of 2-Ethyl hexyl acrylate showing promising qualities were subjected to the determination of their solid content,molecular weight, UV and IR absorption charactersits, peel strength and free monomer content. Local irritation tests on human volunteers indicate their suitability as adhesives.