Antibacterial activity of (e)-4-phenyl-3-buten-2-ones.
College of Pharmaceutical Sciences, K.M.C., Manipal-576 119,
G Elias College of Pharmaceutical Sciences, K.M.C., Manipal-576 119
Antibacterial activity of thirteen substituted phenylbutenones was studied. Regression analysis showed that for the activity against B. subtilis hydrophobicity and electronic parameters are importent. A parabolic model was obtained with hydrophobicity and antibacterial activity against E. coli.