Abstract

Antibacterial activity of (e)-4-phenyl-3-buten-2-ones.

Author(s): G Elias, M NA Rao
College of Pharmaceutical Sciences, K.M.C., Manipal-576 119,

Correspondence Address:
G Elias College of Pharmaceutical Sciences, K.M.C., Manipal-576 119

Antibacterial activity of thirteen substituted phenylbutenones was studied. Regression analysis showed that for the activity against B. subtilis hydrophobicity and electronic parameters are importent. A parabolic model was obtained with hydrophobicity and antibacterial activity against E. coli.