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Abstract

Antibacterial and antiinflammatory activity of some benzimidazoles.

Author(s): AD Deshpande, AV Kasture, AK Dorle
Pravara Rural College of Pharmacy, Pravaranagar, Tal. Shrirampur, Dist. Ahmednagar-413 736

Correspondence Address:
A D Deshpande Pravara Rural College of Pharmacy, Pravaranagar, Tal. Shrirampur, Dist. Ahmednagar-413 736

Benzimidazoles were prepared by Mannich reaction and antibacterial rested against S. aureus, B. subtilis, S. sonnie and A. aerogenes. Antiinflammatory activity of the compound was determined by carragenin-induced rat paw oedema method using a digital plethysmometer. Indomethacin (10 mg/kg) was employed as a standard drug.