Antidiarrhoeal activity of the alcoholic extract of the leaves of Butea frondosa Koen. Ex Roxb.
1 Nalanda College of Pharmacy, Charlapally, Hyderabad Road, Nalgonda-508 001, India 2 Siddaganga College of Pharmacy, B. H. Road, Tumkur-572 102, India 3 Balaji Institute of Pharmaceutical Sciences, Anantpur-515 001, India
D Banji Nalanda College of Pharmacy, Charlapally, Hyderabad Road, Nalgonda-508 001 India E-mail: [email protected]
The study evaluated the antidiarrhoeal property of the alcohol extract of Butea frondosa leaf on mice and rats. Studies revealed that at a dose of 25 and 75 mg/kg a considerable reduction in the extent of diarrhoea was observed but at a dose of 100 mg/kg the animals appeared completely constipated when subjected to castor oil induced diarrhoea and intestinal motility model. Therefore, Butea frondosa can be regarded as an effective antidiarrhoeal.