Abstract

Antifertility activity of cinnamic acids.

Author(s): A Kurup, M NA Rao
College of Pharmaceutical Sciences, K.M.C., Manipal-576 119,

Correspondence Address:
A Kurup College of Pharmaceutical Sciences, K.M.C., Manipal-576 119

Various ring substituted cinnamic acid (CA) derivatives were evaluated for antifertility effect in female albino rats at a dose of 40 mg/kg., i.p., given daily from days 1 to 10 of pregnancy. 3-Nitro-CA., 3,4-dichloro-CA. and CA inhibited pregnancy in 50 percent rats. Rats treated with 3-nitro-CA showed high amount of resorbtion of fetus.