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Abstract

Antifungal potential of some transition metal - chelates of p-amino-salycylic acid (PAS).

Author(s): PV Khadikar, BD Heda, R Saxena, T Khaddar
School of Chemistry, DAVV, 3, Khatipura, Indore - 452 007

Correspondence Address:
P V Khadikar School of Chemistry, DAVV, 3, Khatipura, Indore - 452 007

Metal chelates of P-amino-salycylic acid (PAS) with VO(II),Cu(II),Ni(II)Co(II)Fe(II),Mn(II) and Zn(II) have been prepared and characterised by analytical IR-Spectral and thermal studies. They have been screened for antifungal activities against a series of pathogenic and non-pathogenic fungi. The in vitro filter paper disk method was used exclusively for testing activities. The chelates in comparison to PAS were found to posses remarkable antifungal potential.