All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Antiinflammatory activity of a polyherbal formulation

Author(s): SR Deorukhakar1, A Dethe1, RR Vohra1, R Ghosh1, J Chaudhary2, V Kadam1
1Department of Pharmacology, Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai-400 614, India 2Exotic Naturals, 118 Mourya House, Link Road, Andheri (W), Mumbai-400 053, India

Correspondence Address:
R R Vohra Department of Pharmacology, Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai-400 614 India [email protected]


The antiinflammatory activity of the polyherbal formulation Entox® was investigated in rats for acute and sub acute models of inflammation using carrageenan-induced rat paw edema and cotton pellet granuloma methods respectively at a dose of 300 mg/kg and 600 mg/kg administered orally. The formulation in doses of 300 mg/kg and 600 mg/kg showed 51.61% and 54.84% inhibition of paw edema, respectively at the end of 3 h. The percent inhibition of granuloma by cotton pellet method was 27.92% and 53.17%, respectively. The formulation showed a significant antiinflammatory activity in both the experimental models and the activity was comparable to that of the standard drug, indomethacin.



Share this