Antiinflammatory activity of a polyherbal formulation
1Department of Pharmacology, Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai-400 614, India 2Exotic Naturals, 118 Mourya House, Link Road, Andheri (W), Mumbai-400 053, India
R R Vohra Department of Pharmacology, Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai-400 614 India [email protected]
The antiinflammatory activity of the polyherbal formulation Entox® was investigated in rats for acute and sub acute models of inflammation using carrageenan-induced rat paw edema and cotton pellet granuloma methods respectively at a dose of 300 mg/kg and 600 mg/kg administered orally. The formulation in doses of 300 mg/kg and 600 mg/kg showed 51.61% and 54.84% inhibition of paw edema, respectively at the end of 3 h. The percent inhibition of granuloma by cotton pellet method was 27.92% and 53.17%, respectively. The formulation showed a significant antiinflammatory activity in both the experimental models and the activity was comparable to that of the standard drug, indomethacin.