Abstract

Cow urine distillate appear to possess bioenhancement capacity that increases effectiveness of medicinal products. So, the current research was aimed to evaluate the anti-inflammatory and antioxidant activity of wheat grass powder fortified with cow urine distillate. Antiinflammatory activity was studied using carrageenan-induced paw edema in Wistar rats at 100, 200 and 400 mg/kg doses of wheat grass powder fortified with cow urine distillate and the antioxidant capacity was studied using the ferric thiocyanate method. Wheat grass powder fortified with cow urine distillate showed significant reduction (61.09 %) in peroxide production in the ferric thiocyanate method. All the three doses tested produced significant inhibition of rat paw edema in the carrageenan assay but the 400 mg/kg dose produced maximum inhibition of rat paw edema (40.06 %) at the 5 h time point compared to the control. It is possible to conclude from the results of the study concludes that fortification of wheat grass powder with cow urine distillate enhanced the antioxidant and antiinflammatory activities and further research is necessary to understand the mechanism and phytochemicals responsible for the fortification of the activity of wheat grass.