Antimicrobial Activity Of Notonia Grandiflora DC (Asteraceae)
The in vitro antibacterial activity of Notonia grandiflora (whole plant) has been investigated against Staphylococcus aureus, Shigella shigae, Salmonella typhi, Escherlchia coli, Pseudomouas aeruginosa and Proteus mirablis. The essential oil of the fresh plant at 1:10 dilution showed good activity against S. aureus, S. shigae and P. mirablis almost comparable to the standard antibiotic used. The hexane extract showed good activity and the alcohol extract showed feeble activity against P. mirablis. Friedelin isolated from the hexane extract of the plant showed activity at 1000 ppm against this organism.