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Abstract

Antitumour Property Of Vinblastine Monohydrazide

Author(s): Anny Mathew, G Muraleedhara Kurup, G Jayashree, S Sudarslal, G Vasundhara

The bioconverted product of vinblastine (alkaloid from Vinca raosea), vinblastine monohydrazide was administered to cell line-induced solid tumour in mice and the changes in life span and tumour size were noted. It was found that the bioconverted product was an antitumour agent as it helps in the reduction of solid tumour and also in increasing the life span of tumour induced mice when compared to the crude alkaloid vinblastine.