Assay of tegaserod maleate by difference spectroscopy
Pharmaceutical Quality Assurance Laboratory, Pharmacy Department, Faculty of Technology and Engineering, the M. S. University of Baroda, Vadodara-390 001, India
Sadhana J Rajput Pharmaceutical Quality Assurance Laboratory, Pharmacy Department, the M. S. University of Baroda India E-mail: [email protected]
A simple analytical method for the estimation of tegaserod maleate has been developed to analyze the drug in bulk and in tablet formulation. The method is based on difference spectroscopy and is quite simple, rapid, inexpensive and sensitive. The Beer's law range was followed in the concentration range of 1-30 µg/ml of tegaserod maleate. The molar absorptivity was 1.7920×10 4 l/mole/ cm. The method does not require any separation of soluble excipients as they do not interfere in the estimation.