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Abstract

Cinchophen analogs as analgesic and antiinflammatory agents.

Author(s): P Mishra, RK Agrawal, UK Maini
Dept. of Pharmaceutical Sciences, Doctor Harisingh Gour Vishwavidyalaya, Sagar 470 003 (M.P.),

Correspondence Address:
P Mishra Dept. of Pharmaceutical Sciences, Doctor Harisingh Gour Vishwavidyalaya, Sagar 470 003 (M.P.)

N-Hydroxymethyl derivative of 2-phenyl-4-quinoline carboxamide was prepared and condensed with a few active hydrogen containing compounds (Salicylic acid. Beta-resorcilic acid, phthalimide, phenacetin and acetaminophen). N-hydroxy methyl derivative of cinchophen was found to be a potent analgesic and its product with salicylic acid and Beta-resorcilic acid showed good antiinflammatory activity.