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Abstract

Comparative Antiinflammatory Activity Studies Of Four Species Of Sariva

Author(s): K Lakshman, B Jayaprakash, H Joshi

In the present study, the roots of Sariva (Decalepis hamiltonii, Cryptolepis buchananii, Ichnocarpus frutescens and Hemidesmus indicus) were investigated for antiinflammatory activity in carrageenan- induced rat paw oedema. The ethanol extracts of roots of various species of Sariva exhibited significant antiinflammatory activity at a dose of 350 mg/kg (p.o.) when compared to control group. The activity is compared with standard phenylbutazone. Cryptolepis buchananiiwas found to exhibit significantly more antiinflammatory activity when compared to the other three, Decalepis hamiltonii, lchnocarpus frutescens and Hemidesmus indicus.