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Abstract

Controlled Release Pellets Of Nitrofurantion

Author(s): Rajani Shettigar, A. V Damle

A prototype formula, which is amenable to Spheronization, was designed for the drug cores of Nitrofurantion. Effect of excipient variables and process variables to obtain a product giving desired drug release for a period of 8-10 hours was studied. The successful formulation was subjected to in vitro and in vivo evaluation and stability.