All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Cytotoxic action of ixora javanica leaves.

Author(s): SC Nair, KR Panikkar
Amala Cancer Research Centre, Amala Nagar, Trichur-680 553, (Kerala),

Correspondence Address:
S C Nair Amala Cancer Research Centre, Amala Nagar, Trichur-680 553, (Kerala)

The cytotoxic principles of Ixora javanica was separated from 50 percent ethanol extract by ethyl acetate and purified by paper chromatography using butanol acetic acid water (6:1:2). The active fraction was cytotoxic on DLA EAC and S-180 cells at a concentration of 30;90 and 20 gms respectively. The mechanism of action is probably at the DNA level.