Degradation of some aqueous semi-synthetic penicillin solutions in presence of copper (II) ions.
Hindustan Antibiotics Research Centre, Pimpri, Pune 411 018,
N R Chatterjee Hindustan Antibiotics Research Centre, Pimpri, Pune 411 018
Degradation of aqueous solution of several semi-synthetic penicillins viz. ampicillin, hetacillin, phthalimido penicillin as well as sulfoxides of benzylpenicillin, phthalimide penicillin and ampicillin, in presence of copper (II) ions has been studied following UV-visible spectrophotometric method. Based on these results, comparative studies have been made to evaluate the role of metal ion in affecting the two major pathways responsible for penicillin degardation.