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Abstract

Differential Pulse Polarographic Determination Of 1,4-Benzodiazepine Psychotropic Drugs In Pharmaceutical Formulations And Urine Samples

Author(s): P. R. K Reddy, N. Y Sreedhar, S. J Reddy

A simple, rapid, and sensitive differential pulse polarographic method is developed for the determination of 1,4-benzodiazepine psychotropic drugs such as pinazepam, prazepam and temazepam in pharmaceutical formulations and urine samples, by the aid of universal buffers of pH 2.0 to 12.0.The developed procedure has been applied for the determination of these drugs in pharmaceutical formulations and urine samples as well as simultaneous determination in a single run.