All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Effect of n,n-diethyl phenyl acetamide : an insect repellent on foetus and reproduction in rats.

Author(s): S Prakash, SS Rao, S Kumar, KM Rao
Defence Research and Development Establishment, Gwalior

Correspondence Address:
S Prakash Defence Research and Development Establishment, Gwalior

N, N-Diethyl phenyl acetamide in a dose of 1166.6 mg/kg exerted adverse effect on body weight of adult female rats by 14 days' percutaneous application. A 15 day application of the same dose to pregnant females during gestation period caused intrauterine mortality and lower foetal weight. Lower doses of 583 and 145.9 mg/kg body weight corresponding to 1/3 and 1/12 dermal LD 50 did not have any gross adverse effect on foetus, reproduction or post-natal growth of offsprings.