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Abstract

Effect of solvent composition on the stability of butaperazine dimaleate.

Author(s): GN Singh, RP Gupta
Dept. of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221 005,

Correspondence Address:
G N Singh Dept. of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221 005

Effect of solvent composition on the stability of butaperazine dimaleate is reported. Replacement of medium by 25 percent w/v of dextrose and sucrose increases the rate of degradation of this drug. However, solvent of lower polarity like alcohol and glycerine have shown marked stabilizing effect.