Extractive Spectrophotometric Method For The Determination Of Clarithromycin
A simple extractive spectrophotometric method has been developed for the estimation of clarithromycin in both pure and pharmaceutical dosage forms. The method is based on the formation of an ion-pair complex of the drug with bromocresol green, which is extracted into chloroform. The absorbance of the chloroform layer is measured at 415 nm against a reagent blank. The method has been statistically evaluated.