In vitro screening for antioxidant, antimicrobial, and antidiabetic properties of some Korean native plants on Mt. Halla, Jeju Island
1College of Agricultural, Life and Environmental Sciences, Chungbuk National University, Cheongju 361-763, Republic of Korea 2Research Institute for Hallasan, Jeju 690-816, Republic of Korea 3College of Applied Life Sciences, The Research Institute for Subtropical Agriculture and Biotechnology, Jeju National University, Jeju 690-756, Republic of Korea
J S Kim College of Applied Life Sciences, The Research Institute for Subtropical Agriculture and Biotechnology, Jeju National University, Jeju 690-756 Republic of Korea E-mail: [email protected]
In this study, Prunus padus, Lonicera caerulea, Berberis amurensis, and Ribes maximowiczianum, which are mainly distributed on Mt. Halla, Jeju Island, have been investigated for their antioxidant, antimicrobial, and antidiabetic activities. The methanol extracts of R. maximowiczianum leaves and P. padus branches exhibited significant and dose-dependent antioxidant activity including electron-donation ability and reducing power. To analyze the antimicrobial activity, each extract was tested by a serial two-fold dilution method against five selected gram-positive bacteria and four gram-negative bacteria, and this suggested that P. padus branches possessed the maximum antimicrobial activity against most of the gram-positive bacteria tested. In addition, the methanol extracts of P. padus branches exhibited the highest α-glucosidase inhibitory activity with an IC50value of 1.0±0.1 μg/ml, indicating that P. padus is a promising source as a herbal medicine.