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Abstract

Influence of Calotropis procera roots on biochemistry of reproductive organs of ovariectomized rats

Author(s): D Ahirwar1, Bharti Ahirwar2, MD Kharya3
1 School of Pharmacy, Chouksey Engineering College, Bilaspur - 495 004, India 2 Institute of Pharmaceutical Sciences, Guru Ghasidas, University, Bilaspur - 495 009, India 3 Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar - 470 003, India

Correspondence Address:
D Ahirwar School of Pharmacy, Chouksey Engineering College, Bilaspur - 495 004 India


iochemical alterations have been observed in the uterus, cervix and vagina of ovariectomized rats treated with alcoholic extract of Calotropis procera roots administered in the presence and absence of ethynilestradiol. Ovariectomy resulted in the decrease of glycogen and protein content as well as activity of acid and alkaline phosphatase in the uterus, cervix and vagina. Administration of the alcoholic extract of Calotropis procera increases glycogen and protein content and activity of acid and alkaline phosphatase in uterus and cervix with increasing weights, whereas, the glycogen contents decreased significantly in vagina. Combined treatments of the alcoholic extract with ethynilestradiol act synergistically confirm the estrogenic action of alcoholic extract of Calotropis procera roots in adult ovariectomized rats.



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