All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Interaction between preservatives and pharmaceutical adjuvants : determination of effective concentration

Author(s): RS Thakur, SK Ghosal
Dept. of Pharmacy, Divn. of Pharmaceutics, Jadavpur University, Calcutta-700 032

Correspondence Address:
R S Thakur Dept. of Pharmacy, Divn. of Pharmaceutics, Jadavpur University, Calcutta-700 032

A mathematical relatioship for the interaction between preservatives and pharmaceutical adjuvants has been developed. A linear relationship between the parameter R, i.e. the ratio of total to free preservative concentration and the adjuvant concentration X has been observed. IT is suggested that the R value could be used in calculating the amount of preservative to be used in pharmaceutical formulation.