Mass Spectrometry In Genomics
Mass spectrometry is now an indispensable tool for rapid protein and peptide structural analysis, and the widespread use of mass spectrometry is a reflection of its ability to solve structural problems that are not readily or conclusively determined with conventional techniques. High detection sensitivity and fully automated analysis of many samples in short time has paved way for current proteome research projects. The article gives overview of various mass spectrometry techniques, different methods of sample preparation along with their advantages and disadvantages. The applications based on compatible analytical techniques like liquid chromatography; electrophoresis and surface plasmon resonance coupled to mass spectrometer indicates the wide scope of mass spectrometry.