Modification Of Lactose For Direct Compression - I
An attempt was made to provide cheaper, indigenous, directly compressible lactose by thermal modification of lactose I.P. The modified lactose (Thermally modified lactose, TML) was characterised for physico-chemical properties and flow behaviour and the results compared with those of Marketed directly compressible lactose (MDL). The direct compressibility of TML and MDL was also evaluated by compression on a rotary tablet compression machine. Results indicated TML to be a promising directly compressible excipient which can replace imported directly compressible lactose.