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Abstract

Potent anti-inflammatory 2-(o-hydroxyphenyl)-5-(p-dimethylamino phenyl)-1,3,4-oxadiazoles

Author(s): A Kumar, S Singh, M Verma, AK Saxena, K Shanker
Dept. of Pharmacology and Therapeutics, King George's Medical College, Lucknow

Correspondence Address:
A Kumar Dept. of Pharmacology and Therapeutics, King George's Medical College, Lucknow

2-(Phenyl/o-Hydroxyphenyl)-5-(substituted aryl)-1,3,4-oxadiazoles were synthesised and evaluated for their anti-inflammatory activity and ulcerogenic liability. The most active compound was compared for its anti-inflammatory and ulcerogenic activity with non-steroidal anti-inflammatory drugs (NSAIDS).