Preparation of pellets :extruding and spheronizing machines study.
The Bombay College of Pharmacy, Kalina, Santacruz (E), Bombay-400 098,
H A Doshi The Bombay College of Pharmacy, Kalina, Santacruz (E), Bombay-400 098
The effect of critical variables viz. moisture content (MC) in the extrudate, spheronizer plate speed and spheronization dwell time on the particle size distribution and sphericity of pellets prepared using a Fuji Paudal EXDS-60 extruder and a Fuji Paudal Q-230 spheronizer was studied and the results are presented.