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Abstract

QSAR Comparative Molecular Field Analysis Of Substituted Benzamides As Antiinflammatory Agents

Author(s): Anupama Parate, S. C Chaturvedi, Geeta Kant

A series of N-(4,6-dimethyl-2-pyridlnyl)benzamldeas s non-acidic antiinflammatory drugs was subjected to a 3D-quantitative structure activity relationship using Comparative Molecular Field Analysis. The series was studied with an attempt to derive a co-relationship between biological activity as dependent variable and descriptors as independent variables. The statistical method used was partial least square analysis to ascertain a co-relationship.