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Abstract

Reverse phase HPLC of rifampin-isoniazid mixture in dosage forms

Author(s): PS Mandal, SP Tyagi, SK Talwar
Central Indian Pharmacopoeia Laboratory, Rajnagar, Ghaziabad-201 002

Correspondence Address:
P S Mandal Central Indian Pharmacopoeia Laboratory, Rajnagar, Ghaziabad-201 002

Reverse phase HPLC method has been used for separation of rifampin (RF) and isoniazid (INH) on a mu Bondapak C18 column. A binary mixture of methanol-Water (85:15) was utilised as mobile phase with 254 nm detector.