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Abstract

Reversed phase hplc determination of tonaflate in cream and topical solution.

Author(s): SS Zarapkar, K Athalye
D.G. Ruparel College, Bombay-400 016,

Correspondence Address:
S S Zarapkar D.G. Ruparel College, Bombay-400 016

Tolnaftate (TF) in cream and topical solution was determined by reverse phase HPLC on Partsil-10-ODS column, acetonitrile plus propan-2-ol plus 0.1 N aq. sodium acetate plus water (43:6.2:1:5) as mobile phase, U.V.detection at 254 nm and testosterone valerinate (TV) as internal standard.