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Abstract

Rifampicin pulmospheres for pulmonary delivery

Author(s): MA Morde, AN Bajaj, RS Bhanushali
C. U. Shah College of Pharmacy, S. N. D. T. Women's University, Juhu campus, Santacruz (west), Mumbai-400 049, India

Correspondence Address:
A N Bajaj C. U. Shah College of Pharmacy, S. N. D. T. Women's University, Juhu campus, Santacruz (west), Mumbai-400 049 India [email protected]

Dry powder inhalation formulations of rifampicin were prepared. Spray drying was used to prepare pulmospheres and their physicochemical characteristics were evaluated. Spray dried pulmospheres containing rifampicin were mixed with inhalable lactose for preparing dry powder inhalation formulations. These formulations were further characterized to evaluate the feasibility of developing effective treatments for pulmonary tuberculosis.



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