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Abstract

Simultaneous Determination Of A New Antimalarial Agent, CDRI Compound No 80/53 And Primaquine By TLC Densitometry And UV Spectrophotometry

Author(s): A. K Dwivedi, M Khanna, R Pal, S Singh

Compound 80/53 is a new antimalarial agent developed at C.D.R.I. it is unstable in acidic conditions where it is converted into primaquine. To conduct stability studies of this compound, TLC densitometric and U. V, spectrophotometric estimation methods have been developed. These methods are also suitable for the estimation of 80/53 or primaquine in their dosage forms and bulk drug samples.