Simultaneous Determination Of Salbutamol And Etofylline By Third Derivative Ultraviolet Spectroscopy
Simultaneous determination of salbutamol and etofylline using third derivative ultraviolet spectroscopy with zero crossing technique is reported in this communication. Third derivative amplitudes at 233.8 and 303 nm were selected for the assay of salbutamol and etofylline in combination respectively. This method showed good linearity and precision. The proposed method is successfully applied to the combination of these drugs in laboratory mixture and in tablet dosage form.