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Abstract

Spectrophotofluorometric and fluorodensitometric estimation of allyloestrenol in tablets.

Author(s): P BN Prasad, N Murugesan, A CS Rao, Y Kumar, SC Mathur, Y KS Rathore, PD Sethi
Research & Development Division, Central Indian Pharmacopoeia Laboratory, Ghaziabad - 201 002,

Correspondence Address:
P BN Prasad Research & Development Division, Central Indian Pharmacopoeia Laboratory, Ghaziabad - 201 002

Simple, rapid and senstive spectrophotofluorometric and fluorodensitometric methods for the estimation of allyloestrenol are described. The drug on heating with sulphuric acid reagent in methanol yields a fluorescent derivative which has excitation lamda max at about 292 nm and emission lamda max at about 355 nm. It obeys Beer's law in the concentration range of 0.8 to 8 mcg/ml. Alternatively the drug is quantitated by the use of TLC densitometer (scanner). The methods are found to be accurste.