Spectrophotometric Determination Of Cefadroxil In Dosage Forms
A simple and sensitive spectrophotometric method for the determination of cefadroxil anhydrous and its dosage forms is described. The method is based on the reaction of the drug with Folin-Ciocalteu reagent in presence of sodium hydroxide and stannous chloride to form a blue coloured chromogen having Î»max at 970 nm. The absorbance was found to be linear with the concentration in the range of 5-25 Î¼g/10 ml. The colour developed was stable up to 5 h.