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Abstract

Spectrophotometric Determination Of Cefoperazone Sodium Using Imidazole-Mercury (II) Reagent

Author(s): M. S Raja, P. N. S Pai

A rapid sensitive and simple spectrometric method is developed for the estimation of cefoperazone sodium. It is based on the reaction with imidazole-mercury (II) reagent in slightly acidic medium and heating at 83º for 20 min. The solution has an absorption maxima at 352 nm and obeyed Beer's law in the concentration range of 24-96 µg/ml. Result of analysis were validated statistically and by recovery studies.