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Abstract

Spectrophotometric Determination Of Tizanidine Hydrochloride

Author(s): K Sujatha, K Chitra, D.S Hettiarachchi, M Vinay Krishna, J Vasantha

A new, simple, sensitive spectrophotometric method in ultraviolet region has been developed for the determination of tizanidine hydrochloride in bulk and in dosage form. Tizanidine hydrochloride exhibited maximum absorbance at 320 nm with apparent molar absorptivity of 13.1104x103 I/mol.cm. Beer's law was obeyed in the concentration range of 5-20 μg/ml. Results of the analysis were validated statistically and by recovery studies.