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Abstract

Spectrophotometric estimation of amoxycillin by reaction with diazotized primary aromatic amines

Author(s): JB Dave, SK Banerjee
Pharmacy Department, Faculty of Tech. and Engg., M.S. University of Baroda, Baroda 390 001

Correspondence Address:
J B Dave Pharmacy Department, Faculty of Tech. and Engg., M.S. University of Baroda, Baroda 390 001

A simple, senstive and specific method for estimation of amoxycillin in pharmaceutical dosage forms has been developed by coupling of amoxycillin with different diazotized primary aromatic amines at pH 7.0. Among 12 different amines and amino acids tried, Sulfanilic acid and Sulfanilamide were found to be most suitable.