All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Spectrophotometric methods for the determination of procainamide hydrochloride in tablets.

Author(s): C SP Sastry, TT Rao, A Sailaja, Rao T Thirupathi
Foods and Drugs Laboratory, School of Chemistry, Andhra University,Visakhapatnam-530 003,

Correspondence Address:
C SP Sastry Foods and Drugs Laboratory, School of Chemistry, Andhra University,Visakhapatnam-530 003

Three simple, rapid and senstive spectrophotometric methods are described for the determination of procainamide hydrochloride in bulk samples and pharmaceutical preparations, based on the coupling of the diazotised drug with the reagents such as chromotropic acid, phloroglucinol and ethylacetoacetate to give coloured products having maximum absorbances at 480 nm, 415 nm and 420 nm respectively. The results are reproducible within +/- 1.0 percent