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Abstract

Studies on antibacterial, antifungal and antitumour properties of toluidine blue.

Author(s): S Bandyopadhyay, M Gupta, DK Roy
Dept. of Pharmacy, Jadavpur University, Calcutta-700 032,

Correspondence Address:
S Bandyopadhyay Dept. of Pharmacy, Jadavpur University, Calcutta-700 032

Chemotherapeutic properties of Toluidine Blue, a basic dye have been studied against Gram positive, Gram nagative bacteria, Candida albicans and two transplantable tumour strains of Swiss mice like Ehrlich Ascites Carcinoma and Sarcoma 180. The dye was found to have antibacterial, antifungal and substantial antitumour activities. The LD50 value of Toluidine Blue is 275 mg/kg body weight in albino mice by the intraperitoneal route (i.p.).