Abstract

Study of shellac-glycerol esters as anhydrous binding agents in tablet formulations.

Author(s): VD Labhasetwar, PK Puranik, AK Dorle
Dept. of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010,

Correspondence Address:
V D Labhasetwar Dept. of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010

Shellac-glycerol reaction intermediates were prepared. Tablets were prepared using solutions of these esters as anhydrous binding agents (3.5) and evaluated. The esters exhibited excellent binding properties, imparting hardness to the tablets. The t50 for shellac and SG-33 (acid value 33) is 30 and 28 min. respectively. For other esters t50 lies between 38 to 57 min.