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Abstract

Synthesis and antifungal activity of 2-(4-aryl-2-pyrazolin-3-yl)-3-aryl-4 (3h)-quinazolinones.

Author(s): AM Reddy, RR reddy, VM reddy, Reddy A Malla, Reddy R Raja, Reddy V Malla
Medicinal Chemistry Laboratory, University College of Pharmaceutical Sciences, Kakatiya University, Warangal-506 009, A.P,

Correspondence Address:
A M Reddy Medicinal Chemistry Laboratory, University College of Pharmaceutical Sciences, Kakatiya University, Warangal-506 009, A.P

The title compounds (III) have been prepared by cycloaddition of diazomethane to 3-aryl-2-styryl-4 (3H)-quinazolinones (II) in dry ether. Their structures have been elucidated on the basis of elemental analysis and spectral data (IR, PMR and mass). Some of these compounds have been found to exhibit good antifungal activity.