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Abstract

Synthesis And Biological Evaluation Of 3-(2-Aroyl Aryloxy) Methyl-5-Mercaptc-4H-1,2,4-Triazole Analogues

Author(s): S. A Khanum, S Shashikanth, B. S Sudha

The present investigation was aimed at the synthesis of 3-(2-aroyl aryloxy) methyl-5-mercapto- 4H-1,2,4-triazole analogues 3a-j, by intramolecular cyclization of (2-aroyl aryloxy) acetates 2a-j with thiosemicarbazide. The title compounds were screened for antibacterial, antifungal, anticonvulsant, diuretic and antiinflammatory activities and some of the compounds were found to be active.