All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis And Pharmacological Activities Of Biheterocycles 7-Substitutedphenyl-5-(5'-Substituted-2'-Phenylindol-3'-yl)-1,4-Benzo[b] Diazepines.

Author(s): J. S Biradar, S. Y Manjunath

5-Substituted-2-phenylindol-3-carboxaldehydes (1a-c) were reacted with substituted acetophenones in ethyleneglycol in presence of piperidine to yield the respective chalcones (3ar). When these chalcones were reacted in absolute ethanol with orthophenylene diamine produced 7-substitutedphenyl-5-(5'-substituted-2'-phenylindol-3'-yl)-l,4-benzo[b]diazepines (4a-r). The structures of the newly synthesised compounds were elucidated on the basis of analytical and spectral data. These compounds have been screened for analgesic, antiinflammatory and locomotor activities.

PDF

 
 
Google scholar citation report
Citations : 66710

Indian Journal of Pharmaceutical Sciences received 66710 citations as per google scholar report