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Abstract

Synthesis And Pharmacological Screening Of 5-(4-Aroyl)-Aryloxy Methyl-2-Thio-1, 3,4-Oxadiazole

Author(s): B.S Sudha, S Shashikanth, S.A Khanum, S.N Sriharsha

The title compounds were synthesized by the intramolecular cyclisation of thiosemicarbazides generated by the action of hydrazides 3a-d on carbon disulfide in the presence of potassium hydroxide in good yield. All the compounds have been characterized by elemental analysis and spectral data. All the synthesized compounds were screened for their antibacterial, antifungal, anticonvulsant, antiinflammatory and diuretic activities.