Synthesis and study of n-(2-mercapto-4,5-disubstituted phenyl)-n'-substituted-phenyl thioureas as possible antituberculosis agents.
Dept. of Chemotherapy, Haffkine Institute, Parel, Bombay-12
S M Patil Dept. of Chemotherapy, Haffkine Institute, Parel, Bombay-12
A series of N-(2-mercapto-4,5-disubstituted-phenyl)-N'-substituted phenyl thioureas have been synthesized and screened in vitro against H37 Rv strain of Mycobacteriumtuberculosis. The antitubercular activity of these compounds vary from 50 mug/ml to 0.6 mug/ml.