All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis of some new heterocyclis compounds containing bridgehead nitrogen atom as antifungal drugs.

Author(s): H Singh, KN Shukla, R Dwivedi, L DS Yadav
Dept. of Chemistry, University of Gorakhpur, Gorakhpur 273 009,

Correspondence Address:
H Singh Dept. of Chemistry, University of Gorakhpur, Gorakhpur 273 009

Cyclocondensation of 3-aryl/5-methyl 1-2-hydrazinoimidazol-4-ones II (a-c) with 2,4-dichloro-phenoxy acetic acid, HCOOH, CICO2 ET and CS2 furnished a novel class of compound 7-aryl/5-methyl imidazo [2,1-c] -1,2,4-triazol-6-one and their analogues [III-VI (a-c)]. These have been compared with Diathane M-45, for their antifungal activity against A. niger and F. oxysporum.